UJI TOKSISITAS SUBAKUT EKSTRAK DAUN TEMBAKAU (Nicotiana Tabacum L.) YANG DIFERMENTASI TERHADAP GAMBARAN HISTOLOGI ORGAN VITAL MENCIT(Mus Musculus)

  • Novita Sari Barus
  • Sony Sony STIKes Nurliana Medan
  • Salman Salman Universitas Tjut Nyak Dhien
  • Mahmudi Mahmudi
  • Rita Sunartaty Universitas Serambi Mekkah
Keywords: Uji Toksisitas, Daun Tembakau, Fermentasi

Abstract

Penilitian ini mempunyai tujuan jangka panjang yang ingin di capai adalah mengetahui toksisitas dari tanaman tembakau yang terfermentasi yang diaplikasikan pada mencit, dan melihat histologi dari organ vital pada mencit. Target  khusus  yang  ingin  dicapai  dalam  penelitian  ini  adalah  Mengetahui toksisitas sub akut daun tembakau yang terfermentasi yang diaplikasikan pada mencit, dilihat melalui histologi organ vital mencit, Mengetahui dosis toksin yang ditimbulkan daun tembakau yang terfermentasi untuk kesehatan masyarakat. Metode  yang  akan  di  pakai  untuk  mencapai  tujuan  jangka  panjang  dalam penelitian ini menggunakan penelitian secara eksperimen dengan ketentuan- ketentuan menentukan sampel Mencit (Mus Musculus) , Pengambilan sampel Mencit sebanyak 36 ekor berdasarkan berat badan, jenis kelamin., Pemberian toksin daun tembakau yang terfermentasi terhadap mencit, Pemeriksaan uji toksisitas sub akut terhadap mencit dan melihat histologi organ vita pada mencit.

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Published
2018-12-11